MMACHC FISH Probe
The MMACHC FISH probe is designed to hybridize to the MMACHC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MMACHC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MMACHC-20-RE | 20 (40 μL) | 200 μL |  |
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| MMACHC-20-GO | 20 (40 μL) | 200 μL |  |
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| MMACHC-20-GR | 20 (40 μL) | 200 μL |  |
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| MMACHC-20-AQ | 20 (40 μL) | 200 μL |  |
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| MMACHC-20-DIG | 20 (40 μL) | 200 μL |  |
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| MMACHC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: MMACHC
Gene Name: Methylmalonic Aciduria (cobalamin Deficiency) CblC Type, With Homocystinuria
Chromosome: CHR1: 45965855-45976739
Locus: 1p34.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MMACHC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MMACHC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping