MLLT11 FISH Probe
The MLLT11 FISH probe is designed to hybridize to the MLLT11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MLLT11-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| MLLT11-20-RE | 20 (40 μL) | 200 μL |  |
|
| MLLT11-20-GO | 20 (40 μL) | 200 μL |  |
|
| MLLT11-20-GR | 20 (40 μL) | 200 μL |  |
|
| MLLT11-20-AQ | 20 (40 μL) | 200 μL |  |
|
| MLLT11-20-DIG | 20 (40 μL) | 200 μL |  |
|
| MLLT11-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MLLT11
Gene Name: MLLT11, Transcription Factor 7 Cofactor
Chromosome: CHR1: 151032150-151040973
Locus: 1q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MLLT11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MLLT11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping