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MLLT10 FISH Probe

The MLLT10 FISH probe is designed to hybridize to the MLLT10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MLLT10-20-OR  (Standard Design) 20 (40 μL) 200 μL
MLLT10-20-RE 20 (40 μL) 200 μL
MLLT10-20-GO 20 (40 μL) 200 μL
MLLT10-20-GR 20 (40 μL) 200 μL
MLLT10-20-AQ 20 (40 μL) 200 μL
MLLT10-20-DIG 20 (40 μL) 200 μL
MLLT10-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Gene Details

Gene Symbol: MLLT10

Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor

Chromosome: CHR10: 21823100-22032559

Locus: 10p12.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion Gene

This study investigated a case of myeloid sarcoma (MS), a rare tumor often misdiagnosed as malignant lymphoma, that developed into acute myeloid leukemia (AML). Along with pathologic, morphologic, and immunophenotypic characterization, FISH was used to screen for cytogenetic abnormalities. Our MLLT10 helped detect a rare PICALM-MLLT10 fusion in the patient, an abnormality consistent with disease progression to AML.

Product Details

Product: MLLT10 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MLLT10-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping