MLH3 Break Apart FISH Probe
Empire Genomics’ MLH3 Break Apart FISH Probe is designed to flank the MLH3 gene and is typically used for detecting MLH3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MLH3BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MLH3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MLH3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MLH3BA-20-GORE | 20 (40 μL) | 200 μL |
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| MLH3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MLH3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MLH3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| MLH3BA-20-REGO | 20 (40 μL) | 200 μL |
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| MLH3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MLH3
Gene Name: MutL Homolog 3
Chromosome: CHR14: 75480466-75518235
Locus: 14q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MLH3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MLH3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping