MKRN1 FISH Probe
The MKRN1 FISH probe is designed to hybridize to the MKRN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MKRN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MKRN1-20-RE | 20 (40 μL) | 200 μL |  |
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| MKRN1-20-GO | 20 (40 μL) | 200 μL |  |
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| MKRN1-20-GR | 20 (40 μL) | 200 μL |  |
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| MKRN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MKRN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MKRN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: MKRN1
Gene Name: Makorin Ring Finger Protein 1
Chromosome: CHR7: 140152839-140179369
Locus: 7q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MKRN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MKRN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping