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MKRN1 FISH Probe

The MKRN1 FISH probe is designed to hybridize to the MKRN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MKRN1-20-OR  (Standard Design) 20 (40 μL) 200 μL
MKRN1-20-RE 20 (40 μL) 200 μL
MKRN1-20-GO 20 (40 μL) 200 μL
MKRN1-20-GR 20 (40 μL) 200 μL
MKRN1-20-AQ 20 (40 μL) 200 μL
MKRN1-20-DIG 20 (40 μL) 200 μL
MKRN1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

Gene Details

Gene Symbol: MKRN1

Gene Name: Makorin Ring Finger Protein 1

Chromosome: CHR7: 140152839-140179369

Locus: 7q34

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MKRN1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MKRN1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping