MIR4458 Break Apart FISH Probe
Empire Genomics’ MIR4458 Break Apart FISH Probe is designed to flank the MIR4458 gene and is typically used for detecting MIR4458 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MIR4458BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-GORE | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-GROR | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-REGO | 20 (40 μL) | 200 μL |
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| MIR4458BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: MIR4458
Gene Name: MicroRNA 4458
Chromosome: CHR5: 8461037-8461112
Locus: 5p15.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MIR4458 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MIR4458-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping