MIR34A Break Apart FISH Probe
Empire Genomics’ MIR34A Break Apart FISH Probe is designed to flank the MIR34A gene and is typically used for detecting MIR34A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MIR34ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-GORE | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-REGO | 20 (40 μL) | 200 μL |
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| MIR34ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. This miRNA is a member of the highly conserved miR-34 family. This miRNA functions as a tumor suppressor and dysregulation or loss of the host gene from which this miRNA is processed is associated with cancer progression in numerous cell types. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: MIR34A
Gene Name: MicroRNA 34a
Chromosome: CHR1: 9211726-9211836
Locus: 1p36.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MIR34A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MIR34A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping