METNASE FISH Probe
The METNASE FISH probe is designed to hybridize to the METNASE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SETMAR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| SETMAR-20-RE | 20 (40 μL) | 200 μL |  |
|
| SETMAR-20-GO | 20 (40 μL) | 200 μL |  |
|
| SETMAR-20-GR | 20 (40 μL) | 200 μL |  |
|
| SETMAR-20-AQ | 20 (40 μL) | 200 μL |  |
|
| SETMAR-20-DIG | 20 (40 μL) | 200 μL |  |
|
| SETMAR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Details
Gene Symbol: SETMAR
Gene Name: SET Domain And Mariner Transposase Fusion Gene
Chromosome: CHR3: 4344987-4358949
Locus: 3p26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: METNASE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SETMAR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping