METAP2 Break Apart FISH Probe
Empire Genomics’ METAP2 Break Apart FISH Probe is designed to flank the METAP2 gene and is typically used for detecting METAP2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| METAP2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| METAP2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| METAP2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| METAP2BA-20-GORE | 20 (40 μL) | 200 μL |
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| METAP2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| METAP2BA-20-GROR | 20 (40 μL) | 200 μL |
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| METAP2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| METAP2BA-20-REGO | 20 (40 μL) | 200 μL |
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| METAP2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: METAP2
Gene Name: Methionyl Aminopeptidase 2
Chromosome: CHR12: 95867821-95909613
Locus: 12q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: METAP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: METAP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping