METAP2 FISH Probe
The METAP2 FISH probe is designed to hybridize to the METAP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| METAP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| METAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| METAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| METAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| METAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| METAP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| METAP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: METAP2
Gene Name: Methionyl Aminopeptidase 2
Chromosome: CHR12: 95867821-95909613
Locus: 12q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: METAP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: METAP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping