MET Break Apart FISH Probe
Empire Genomics’ MET Break Apart FISH Probe is designed to flank the MET gene and is typically used for detecting MET rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| METBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| METBA-20-AQOR | 20 (40 μL) | 200 μL |
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| METBA-20-GOGR | 20 (40 μL) | 200 μL |
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| METBA-20-GORE | 20 (40 μL) | 200 μL |
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| METBA-20-GRGO | 20 (40 μL) | 200 μL |
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| METBA-20-GROR | 20 (40 μL) | 200 μL |
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| METBA-20-GRRE | 20 (40 μL) | 200 μL |
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| METBA-20-REGO | 20 (40 μL) | 200 μL |
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| METBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
Gene Details
Gene Symbol: MET
Gene Name: MET Proto-oncogene, Receptor Tyrosine Kinase
Chromosome: CHR7: 116312458-116438440
Locus: 7q31.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MET FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MET-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping