MEP1B FISH Probe
The MEP1B FISH probe is designed to hybridize to the MEP1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MEP1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MEP1B-20-RE | 20 (40 μL) | 200 μL |  |
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| MEP1B-20-GO | 20 (40 μL) | 200 μL |  |
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| MEP1B-20-GR | 20 (40 μL) | 200 μL |  |
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| MEP1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| MEP1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| MEP1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]
Gene Details
Gene Symbol: MEP1B
Gene Name: Meprin A Subunit Beta
Chromosome: CHR18: 29769986-29800366
Locus: 18q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MEP1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MEP1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping