MELIOS FISH Probe
The MELIOS FISH probe is designed to hybridize to the MELIOS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TLR5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TLR5-20-RE | 20 (40 μL) | 200 μL |  |
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| TLR5-20-GO | 20 (40 μL) | 200 μL |  |
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| TLR5-20-GR | 20 (40 μL) | 200 μL |  |
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| TLR5-20-AQ | 20 (40 μL) | 200 μL |  |
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| TLR5-20-DIG | 20 (40 μL) | 200 μL |  |
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| TLR5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
Gene Details
Gene Symbol: TLR5
Gene Name: Toll Like Receptor 5
Chromosome: CHR1: 223282747-223316624
Locus: 1q41
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MELIOS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TLR5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping