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MEL1 FISH Probe

The MEL1 FISH probe is designed to hybridize to the MEL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PRDM16-20-OR  (Standard Design) 20 (40 μL) 200 μL
PRDM16-20-RE 20 (40 μL) 200 μL
PRDM16-20-GO 20 (40 μL) 200 μL
PRDM16-20-GR 20 (40 μL) 200 μL
PRDM16-20-AQ 20 (40 μL) 200 μL
PRDM16-20-DIG 20 (40 μL) 200 μL
PRDM16-20-BIO 20 (40 μL) 200 μL

Gene Summary

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PRDM16

Gene Name: PR/SET Domain 16

Chromosome: CHR1: 2985741-3355185

Locus: 1p36.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MEL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PRDM16-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping