MEL FISH Probe
The MEL FISH probe is designed to hybridize to the MEL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAB8A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RAB8A-20-RE | 20 (40 μL) | 200 μL |  |
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| RAB8A-20-GO | 20 (40 μL) | 200 μL |  |
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| RAB8A-20-GR | 20 (40 μL) | 200 μL |  |
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| RAB8A-20-AQ | 20 (40 μL) | 200 μL |  |
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| RAB8A-20-DIG | 20 (40 μL) | 200 μL |  |
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| RAB8A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RAB8A
Gene Name: RAB8A, Member RAS Oncogene Family
Chromosome: CHR19: 16222489-16244445
Locus: 19p13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MEL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAB8A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping