MDS FISH Probe
The MDS FISH probe is designed to hybridize to the MDS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SF3B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SF3B1-20-RE | 20 (40 μL) | 200 μL |  |
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| SF3B1-20-GO | 20 (40 μL) | 200 μL |  |
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| SF3B1-20-GR | 20 (40 μL) | 200 μL |  |
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| SF3B1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SF3B1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SF3B1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SF3B1
Gene Name: Splicing Factor 3b Subunit 1
Chromosome: CHR2: 198256697-198299771
Locus: 2q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MDS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SF3B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping