MDM2 Break Apart FISH Probe
Empire Genomics’ MDM2 Break Apart FISH Probe is designed to flank the MDM2 gene and is typically used for detecting MDM2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MDM2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MDM2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MDM2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MDM2BA-20-GORE | 20 (40 μL) | 200 μL |
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| MDM2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MDM2BA-20-GROR | 20 (40 μL) | 200 μL |
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| MDM2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MDM2BA-20-REGO | 20 (40 μL) | 200 μL |
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| MDM2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Gene Details
Gene Symbol: MDM2
Gene Name: MDM2 Proto-oncogene
Chromosome: CHR12: 69201970-69239212
Locus: 12q15
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MDM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MDM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping