MDM2 FISH Probe
The MDM2 FISH probe is designed to hybridize to the MDM2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MDM2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MDM2-20-RE | 20 (40 μL) | 200 μL |  |
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| MDM2-20-GO | 20 (40 μL) | 200 μL |  |
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| MDM2-20-GR | 20 (40 μL) | 200 μL |  |
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| MDM2-20-AQ | 20 (40 μL) | 200 μL |  |
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| MDM2-20-DIG | 20 (40 μL) | 200 μL |  |
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| MDM2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Gene Details
Gene Symbol: MDM2
Gene Name: MDM2 Proto-oncogene
Chromosome: CHR12: 69201970-69239212
Locus: 12q15
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MDM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MDM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping