MDC1 FISH Probe
The MDC1 FISH probe is designed to hybridize to the MDC1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MDC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MDC1-20-RE | 20 (40 μL) | 200 μL |  |
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| MDC1-20-GO | 20 (40 μL) | 200 μL |  |
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| MDC1-20-GR | 20 (40 μL) | 200 μL |  |
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| MDC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MDC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MDC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MDC1
Gene Name: Mediator Of DNA Damage Checkpoint 1
Chromosome: CHR6_ssto_hap7: 1999890-2017765
Locus: 6p21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MDC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MDC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping