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MCM4 FISH Probe

The MCM4 FISH probe is designed to hybridize to the MCM4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
MCM4-20-OR  (Standard Design) 20 (40 μL) 200 μL
MCM4-20-RE 20 (40 μL) 200 μL
MCM4-20-GO 20 (40 μL) 200 μL
MCM4-20-GR 20 (40 μL) 200 μL
MCM4-20-AQ 20 (40 μL) 200 μL
MCM4-20-DIG 20 (40 μL) 200 μL
MCM4-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: MCM4

Gene Name: Minichromosome Maintenance Complex Component 4

Chromosome: CHR8: 48872762-48890719

Locus: 8q11.21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MCM4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MCM4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping