MCM3AP Break Apart FISH Probe
Empire Genomics’ MCM3AP Break Apart FISH Probe is designed to flank the MCM3AP gene and is typically used for detecting MCM3AP rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MCM3APBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MCM3APBA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: MCM3AP
Gene Name: Minichromosome Maintenance Complex Component 3 Associated Protein
Chromosome: CHR21: 47655047-47705236
Locus: 21q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MCM3AP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MCM3AP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping