MCM3 Break Apart FISH Probe
Empire Genomics’ MCM3 Break Apart FISH Probe is designed to flank the MCM3 gene and is typically used for detecting MCM3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MCM3BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MCM3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MCM3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MCM3BA-20-GORE | 20 (40 μL) | 200 μL |
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| MCM3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MCM3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MCM3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| MCM3BA-20-REGO | 20 (40 μL) | 200 μL |
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| MCM3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: MCM3
Gene Name: Minichromosome Maintenance Complex Component 3
Chromosome: CHR6: 52128811-52149582
Locus: 6p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MCM3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MCM3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping