MBP1 FISH Probe
The MBP1 FISH probe is designed to hybridize to the MBP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRG2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRG2-20-RE | 20 (40 μL) | 200 μL |  |
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| PRG2-20-GO | 20 (40 μL) | 200 μL |  |
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| PRG2-20-GR | 20 (40 μL) | 200 μL |  |
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| PRG2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRG2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRG2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: PRG2
Gene Name: Proteoglycan 2, Pro Eosinophil Major Basic Protein
Chromosome: CHR11: 57154833-57158130
Locus: 11q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MBP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRG2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping