MBP Break Apart FISH Probe
Empire Genomics’ MBP Break Apart FISH Probe is designed to flank the MBP gene and is typically used for detecting MBP rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MBPBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MBPBA-20-AQOR | 20 (40 μL) | 200 μL |
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| MBPBA-20-GOGR | 20 (40 μL) | 200 μL |
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| MBPBA-20-GORE | 20 (40 μL) | 200 μL |
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| MBPBA-20-GRGO | 20 (40 μL) | 200 μL |
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| MBPBA-20-GRRE | 20 (40 μL) | 200 μL |
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| MBPBA-20-ORGR | 20 (40 μL) | 200 μL |
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| MBPBA-20-REGO | 20 (40 μL) | 200 μL |
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| MBPBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MBP
Gene Name: Myelin Basic Protein
Chromosome: CHR18: 74690788-74844774
Locus: 18q23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MBP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MBP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping