MBP FISH Probe
The MBP FISH probe is designed to hybridize to the MBP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MBP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MBP-20-RE | 20 (40 μL) | 200 μL |  |
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| MBP-20-GO | 20 (40 μL) | 200 μL |  |
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| MBP-20-GR | 20 (40 μL) | 200 μL |  |
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| MBP-20-AQ | 20 (40 μL) | 200 μL |  |
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| MBP-20-DIG | 20 (40 μL) | 200 μL |  |
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| MBP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MBP
Gene Name: Myelin Basic Protein
Chromosome: CHR18: 74690788-74844774
Locus: 18q23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MBP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MBP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping