MBNL1 Break Apart FISH Probe
Empire Genomics’ MBNL1 Break Apart FISH Probe is designed to flank the MBNL1 gene and is typically used for detecting MBNL1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MBNL1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-GORE | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-GROR | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-REGO | 20 (40 μL) | 200 μL |
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| MBNL1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: MBNL1
Gene Name: Muscleblind Like Splicing Regulator 1
Chromosome: CHR3: 151985828-152183568
Locus: 3q25.1-q25.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MBNL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MBNL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping