The MBD5 FISH probe is designed to hybridize to the MBD5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MBD5-20-OR  (Standard Design) 20 (40 μL) 200 μL
MBD5-20-RE 20 (40 μL) 200 μL
MBD5-20-GO 20 (40 μL) 200 μL
MBD5-20-GR 20 (40 μL) 200 μL
MBD5-20-AQ 20 (40 μL) 200 μL
MBD5-20-DIG 20 (40 μL) 200 μL
MBD5-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause an autosomal dominant type of cognitive disability. The encoded protein interacts with the polycomb repressive complex PR-DUB which catalyzes the deubiquitination of a lysine residue of histone 2A. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq, Jul 2017]

Gene Details

Gene Symbol: MBD5

Gene Name: Methyl-CpG Binding Domain Protein 5

Chromosome: CHR2: 148778579-149271044

Locus: 2q23.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MBD5 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL


Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping