MBD1 FISH Probe
The MBD1 FISH probe is designed to hybridize to the MBD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MBD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| MBD1-20-RE | 20 (40 μL) | 200 μL |  |
|
| MBD1-20-GO | 20 (40 μL) | 200 μL |  |
|
| MBD1-20-GR | 20 (40 μL) | 200 μL |  |
|
| MBD1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| MBD1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| MBD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: MBD1
Gene Name: Methyl-CpG Binding Domain Protein 1
Chromosome: CHR18: 47793251-47808144
Locus: 18q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MBD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MBD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping