MAPKBP1 Break Apart FISH Probe
Empire Genomics’ MAPKBP1 Break Apart FISH Probe is designed to flank the MAPKBP1 gene and is typically used for detecting MAPKBP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPKBP1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-GROR | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| MAPKBP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: MAPKBP1
Gene Name: Mitogen-activated Protein Kinase Binding Protein 1
Chromosome: CHR15: 42066631-42120053
Locus: 15q15.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPKBP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPKBP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping