MAPKAPK5 Break Apart FISH Probe
Empire Genomics’ MAPKAPK5 Break Apart FISH Probe is designed to flank the MAPKAPK5 gene and is typically used for detecting MAPKAPK5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPKAPK5BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-GORE | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-GROR | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-REGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
Gene Details
Gene Symbol: MAPKAPK5
Gene Name: Mitogen-activated Protein Kinase-activated Protein Kinase 5
Chromosome: CHR12: 112280278-112331228
Locus: 12q24.12-q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPKAPK5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPKAPK5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping