MAPKAPK3 Break Apart FISH Probe
Empire Genomics’ MAPKAPK3 Break Apart FISH Probe is designed to flank the MAPKAPK3 gene and is typically used for detecting MAPKAPK3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPKAPK3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-GORE | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-GROR | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-REGO | 20 (40 μL) | 200 μL |
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| MAPKAPK3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: MAPKAPK3
Gene Name: Mitogen-activated Protein Kinase-activated Protein Kinase 3
Chromosome: CHR3: 50649292-50686728
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPKAPK3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPKAPK3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping