MAPKAPK-5 FISH Probe
The MAPKAPK-5 FISH probe is designed to hybridize to the MAPKAPK-5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPKAPK5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPKAPK5-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPKAPK5-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPKAPK5-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPKAPK5-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPKAPK5-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPKAPK5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
Gene Details
Gene Symbol: MAPKAPK5
Gene Name: Mitogen-activated Protein Kinase-activated Protein Kinase 5
Chromosome: CHR12: 112280278-112331228
Locus: 12q24.12-q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPKAPK-5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPKAPK5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping