MAPK14 FISH Probe
The MAPK14 FISH probe is designed to hybridize to the MAPK14 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPK14-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPK14-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPK14-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPK14-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPK14-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPK14-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPK14-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MAPK14
Gene Name: Mitogen-activated Protein Kinase 14
Chromosome: CHR6: 35995453-36079013
Locus: 6p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPK14 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPK14-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping