MAPK1 Break Apart FISH Probe
Empire Genomics’ MAPK1 Break Apart FISH Probe is designed to flank the MAPK1 gene and is typically used for detecting MAPK1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPK1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-GORE | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-REGO | 20 (40 μL) | 200 μL |
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| MAPK1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: MAPK1
Gene Name: Mitogen-activated Protein Kinase 1
Chromosome: CHR22: 22113946-22221970
Locus: 22q11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPK1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping