MANEA FISH Probe
The MANEA FISH probe is designed to hybridize to the MANEA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MANEA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MANEA-20-RE | 20 (40 μL) | 200 μL |  |
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| MANEA-20-GO | 20 (40 μL) | 200 μL |  |
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| MANEA-20-GR | 20 (40 μL) | 200 μL |  |
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| MANEA-20-AQ | 20 (40 μL) | 200 μL |  |
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| MANEA-20-DIG | 20 (40 μL) | 200 μL |  |
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| MANEA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008]
Gene Details
Gene Symbol: MANEA
Gene Name: Mannosidase Endo-alpha
Chromosome: CHR6: 96025372-96057328
Locus: 6q16.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MANEA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MANEA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping