MAN2B1 FISH Probe
The MAN2B1 FISH probe is designed to hybridize to the MAN2B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAN2B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAN2B1-20-RE | 20 (40 μL) | 200 μL |  |
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| MAN2B1-20-GO | 20 (40 μL) | 200 μL |  |
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| MAN2B1-20-GR | 20 (40 μL) | 200 μL |  |
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| MAN2B1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAN2B1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAN2B1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: MAN2B1
Gene Name: Mannosidase Alpha Class 2B Member 1
Chromosome: CHR19: 12757321-12777591
Locus: 19p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAN2B1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAN2B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping