MAN1B1 FISH Probe
The MAN1B1 FISH probe is designed to hybridize to the MAN1B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MAN1B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
MAN1B1-20-RE | 20 (40 μL) | 200 μL | ||
MAN1B1-20-GO | 20 (40 μL) | 200 μL | ||
MAN1B1-20-GR | 20 (40 μL) | 200 μL | ||
MAN1B1-20-AQ | 20 (40 μL) | 200 μL | ||
MAN1B1-20-DIG | 20 (40 μL) | 200 μL | ||
MAN1B1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Gene Details
Gene Symbol: MAN1B1
Gene Name: Mannosidase Alpha Class 1B Member 1
Chromosome: CHR9: 139981416-140003639
Locus: 9q34.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAN1B1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAN1B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping