MAM FISH Probe
The MAM FISH probe is designed to hybridize to the MAM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PZP-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
PZP-20-RE | 20 (40 μL) | 200 μL | ||
PZP-20-GO | 20 (40 μL) | 200 μL | ||
PZP-20-GR | 20 (40 μL) | 200 μL | ||
PZP-20-AQ | 20 (40 μL) | 200 μL | ||
PZP-20-DIG | 20 (40 μL) | 200 μL | ||
PZP-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients. [provided by RefSeq, Dec 2016]
Gene Details
Gene Symbol: PZP
Gene Name: PZP, Alpha-2-macroglobulin Like
Chromosome: CHR12: 9301435-9360966
Locus: 12p13.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: MAM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PZP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping