MAGEL2 FISH Probe
The MAGEL2 FISH probe is designed to hybridize to the MAGEL2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAGEL2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAGEL2-20-RE | 20 (40 μL) | 200 μL |  |
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| MAGEL2-20-GO | 20 (40 μL) | 200 μL |  |
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| MAGEL2-20-GR | 20 (40 μL) | 200 μL |  |
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| MAGEL2-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAGEL2-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAGEL2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010]
Gene Details
Gene Symbol: MAGEL2
Gene Name: MAGE Family Member L2
Chromosome: CHR15: 23888695-23892993
Locus: 15q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAGEL2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAGEL2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping