MADD FISH Probe
The MADD FISH probe is designed to hybridize to the MADD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MADD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MADD-20-RE | 20 (40 μL) | 200 μL |  |
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| MADD-20-GO | 20 (40 μL) | 200 μL |  |
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| MADD-20-GR | 20 (40 μL) | 200 μL |  |
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| MADD-20-AQ | 20 (40 μL) | 200 μL |  |
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| MADD-20-DIG | 20 (40 μL) | 200 μL |  |
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| MADD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MADD
Gene Name: MAP Kinase Activating Death Domain
Chromosome: CHR11: 47290926-47351582
Locus: 11p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MADD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MADD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping