M-OR-1 FISH Probe
The M-OR-1 FISH probe is designed to hybridize to the M-OR-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
OPRM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
OPRM1-20-RE | 20 (40 μL) | 200 μL | ||
OPRM1-20-GO | 20 (40 μL) | 200 μL | ||
OPRM1-20-GR | 20 (40 μL) | 200 μL | ||
OPRM1-20-AQ | 20 (40 μL) | 200 μL | ||
OPRM1-20-DIG | 20 (40 μL) | 200 μL | ||
OPRM1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]
Gene Details
Gene Symbol: OPRM1
Gene Name: Opioid Receptor Mu 1
Chromosome: CHR6: 154360442-154568001
Locus: 6q25.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: M-OR-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OPRM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping