LZTFL1 Break Apart FISH Probe
Empire Genomics’ LZTFL1 Break Apart FISH Probe is designed to flank the LZTFL1 gene and is typically used for detecting LZTFL1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LZTFL1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| LZTFL1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Gene Details
Gene Symbol: LZTFL1
Gene Name: Leucine Zipper Transcription Factor Like 1
Chromosome: CHR3: 45865445-45883621
Locus: 3p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: LZTFL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LZTFL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping