LXR FISH Probe
The LXR FISH probe is designed to hybridize to the LXR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NR1H2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NR1H2-20-RE | 20 (40 μL) | 200 μL |  |
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| NR1H2-20-GO | 20 (40 μL) | 200 μL |  |
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| NR1H2-20-GR | 20 (40 μL) | 200 μL |  |
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| NR1H2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NR1H2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NR1H2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Gene Details
Gene Symbol: NR1H2
Gene Name: Nuclear Receptor Subfamily 1 Group H Member 2
Chromosome: CHR19: 50879684-50886267
Locus: 19q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LXR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NR1H2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping