LRP6 FISH Probe
The LRP6 FISH probe is designed to hybridize to the LRP6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRP6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LRP6-20-RE | 20 (40 μL) | 200 μL |  |
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| LRP6-20-GO | 20 (40 μL) | 200 μL |  |
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| LRP6-20-GR | 20 (40 μL) | 200 μL |  |
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| LRP6-20-AQ | 20 (40 μL) | 200 μL |  |
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| LRP6-20-DIG | 20 (40 μL) | 200 μL |  |
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| LRP6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
Gene Details
Gene Symbol: LRP6
Gene Name: LDL Receptor Related Protein 6
Chromosome: CHR12: 12268960-12419811
Locus: 12p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LRP6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LRP6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping