LRP1 Break Apart FISH Probe
Empire Genomics’ LRP1 Break Apart FISH Probe is designed to flank the LRP1 gene and is typically used for detecting LRP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRP1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| LRP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| LRP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| LRP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| LRP1BA-20-GROR | 20 (40 μL) | 200 μL |
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| LRP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| LRP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| LRP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: LRP1
Gene Name: LDL Receptor Related Protein 1
Chromosome: CHR12: 57522281-57607125
Locus: 12q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LRP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LRP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping