LOXHD1 Break Apart FISH Probe
Empire Genomics’ LOXHD1 Break Apart FISH Probe is designed to flank the LOXHD1 gene and is typically used for detecting LOXHD1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LOXHD1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-GORE | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-REGO | 20 (40 μL) | 200 μL |
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| LOXHD1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a highly conserved protein consisting entirely of PLAT (polycystin/lipoxygenase/alpha-toxin) domains, thought to be involved in targeting proteins to the plasma membrane. Studies in mice show that this gene is expressed in the mechanosensory hair cells in the inner ear, and mutations in this gene lead to auditory defects, indicating that this gene is essential for normal hair cell function. Screening of human families segregating deafness identified a mutation in this gene which causes DFNB77, a progressive form of autosomal-recessive nonsyndromic hearing loss (ARNSHL). Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: LOXHD1
Gene Name: Lipoxygenase Homology Domains 1
Chromosome: CHR18: 44057216-44236996
Locus: 18q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LOXHD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LOXHD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping