LOW QUALITY PROTEIN: DENN FISH Probe
The LOW QUALITY PROTEIN: DENN FISH probe is designed to hybridize to the LOW QUALITY PROTEIN: DENN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DENND5A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DENND5A-20-RE | 20 (40 μL) | 200 μL |  |
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| DENND5A-20-GO | 20 (40 μL) | 200 μL |  |
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| DENND5A-20-GR | 20 (40 μL) | 200 μL |  |
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| DENND5A-20-AQ | 20 (40 μL) | 200 μL |  |
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| DENND5A-20-DIG | 20 (40 μL) | 200 μL |  |
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| DENND5A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017]
Gene Details
Gene Symbol: DENND5A
Gene Name: DENN Domain Containing 5A
Chromosome: CHR11: 9160374-9286873
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LOW QUALITY PROTEIN: DENN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DENND5A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping