LONM FISH Probe
The LONM FISH probe is designed to hybridize to the LONM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LONP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LONP1-20-RE | 20 (40 μL) | 200 μL |  |
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| LONP1-20-GO | 20 (40 μL) | 200 μL |  |
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| LONP1-20-GR | 20 (40 μL) | 200 μL |  |
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| LONP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LONP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LONP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Details
Gene Symbol: LONP1
Gene Name: Lon Peptidase 1, Mitochondrial
Chromosome: CHR19: 5691844-5720176
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LONM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LONP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping