LMOD3 FISH Probe
The LMOD3 FISH probe is designed to hybridize to the LMOD3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LMOD3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LMOD3-20-RE | 20 (40 μL) | 200 μL |  |
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| LMOD3-20-GO | 20 (40 μL) | 200 μL |  |
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| LMOD3-20-GR | 20 (40 μL) | 200 μL |  |
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| LMOD3-20-AQ | 20 (40 μL) | 200 μL |  |
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| LMOD3-20-DIG | 20 (40 μL) | 200 μL |  |
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| LMOD3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: LMOD3
Gene Name: Leiomodin 3
Chromosome: CHR3: 69156038-69171746
Locus: 3p14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LMOD3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LMOD3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping