LIN-28 FISH Probe
The LIN-28 FISH probe is designed to hybridize to the LIN-28 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LIN28B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LIN28B-20-RE | 20 (40 μL) | 200 μL |  |
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| LIN28B-20-GO | 20 (40 μL) | 200 μL |  |
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| LIN28B-20-GR | 20 (40 μL) | 200 μL |  |
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| LIN28B-20-AQ | 20 (40 μL) | 200 μL |  |
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| LIN28B-20-DIG | 20 (40 μL) | 200 μL |  |
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| LIN28B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Gene Details
Gene Symbol: LIN28B
Gene Name: Lin-28 Homolog B
Chromosome: CHR6: 105404922-105531206
Locus: 6q16.3-q21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LIN-28 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LIN28B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping